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首页> 外文OA文献 >Grading quality of evidence and strength of recommendations in clinical practice guidelines part 3 of 3. The GRADE approach to developing recommendations.
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Grading quality of evidence and strength of recommendations in clinical practice guidelines part 3 of 3. The GRADE approach to developing recommendations.

机译：临床实践指南中第3部分（共3部分）的证据质量和建议强度的分级。GRADE制定建议的方法。

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摘要

This is the third and last article in the series about the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to grading the quality of evidence and the strength of recommendations in clinical practice guidelines and its application in the field of allergy. We describe the factors that influence the strength of recommendations about the use of diagnostic, preventive and therapeutic interventions: the balance of desirable and undesirable consequences, the quality of a body of evidence related to a decision, patients' values and preferences, and considerations of resource use. We provide examples from two recently developed guidelines in the field of allergy that applied the GRADE approach. The main advantages of this approach are the focus on patient important outcomes, explicit consideration of patients' values and preferences, the systematic approach to collecting the evidence, the clear separation of the concepts of quality of evidence and strength of recommendations, and transparent reporting of the decision process. The focus on transparency facilitates understanding and implementation and should empower patients, clinicians and other health care professionals to make informed choices.
机译：这是有关建议评估，开发和评估分级（GRADE）方法的系列的第三篇也是最后一篇文章，该方法用于对证据质量和推荐强度在临床实践指南中的应用及其在过敏领域的应用进行分级。我们描述了影响有关使用诊断，预防和治疗干预措施的建议强度的因素：理想和不良后果之间的平衡，与决策相关的证据质量，患者的价值观和偏好以及对以下方面的考虑资源使用。我们提供了两个最近在过敏领域应用GRADE方法开发的指南中的示例。这种方法的主要优点是关注患者的重要结果，明确考虑患者的价值观和偏好，系统地收集证据，明确区分证据质量和建议强度的概念以及透明地报告决策过程。注重透明性有助于理解和实施，并应使患者，临床医生和其他卫生保健专业人员能够做出明智的选择。

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